Are you dreaming of the ultimate African safari adventure? Whether you’re searching for the Big Five, staying in luxury safari lodges, or chasing the Great Migration, Africa offers some of the most unforgettable wildlife experiences on Earth. In this guide, we explore the top safari destinations in Africa, highlighting the best national parks and game reserves to visit in 2025 and beyond.
Best for: The Great Migration, Big Five, luxury tented camps
The Masai Mara is one of the most iconic safari destinations in Africa. Known for the annual Great Migration, where over two million wildebeest and zebra cross from Tanzania’s Serengeti into Kenya, this park offers dramatic predator-prey action. You’ll have excellent chances of seeing lions, elephants, leopards, rhinos, and buffaloes—making it a top location for a Big Five safari.
Top experiences: Hot air balloon safaris, luxury safari lodges, Maasai cultural tours
Best time to visit: July to October (for the migration)
Best for: Budget-friendly safaris, self-drive options, diverse wildlife
Kruger National Park is South Africa’s premier safari destination and one of the largest game reserves in Africa. With excellent infrastructure, it’s perfect for first-time visitors looking for affordable African safari tours. You’ll find a wide variety of accommodations, from budget camps to 5-star safari lodges.
Top experiences: Self-drive safaris, guided game drives, birdwatching
Best time to visit: May to September (dry season)
Best for: Wildlife photography, Great Migration, endless savannahs
Home to the other half of the Great Migration, the Serengeti is world-renowned for its vast plains and rich biodiversity. It’s one of the best safari destinations in Africa for spotting predators in action, particularly cheetahs and lions.
Top experiences: Mobile camping safaris, photographic safaris, hot air balloon rides
Best time to visit: June to October (dry season); January to March (calving season)
Best for: Water-based safaris, untouched wilderness, exclusive experiences
A UNESCO World Heritage Site, the Okavango Delta offers a unique safari experience with its lush wetlands, meandering waterways, and incredible wildlife. Enjoy mokoro (dugout canoe) safaris, walking safaris, and intimate game viewing in one of the most pristine ecosystems in the world.
Top experiences: Water safaris, birdwatching, luxury tented camps
Best time to visit: June to October (when floodwaters attract wildlife)
Best for: Unique landscapes, salt pans, easy wildlife viewing
Etosha stands out with its striking white salt pan and excellent viewing around waterholes. Wildlife tends to congregate at these spots, making it easier to see elephants, lions, and rare species like black rhinos and gemsbok.
Top experiences: Self-drive safaris, night drives, photography tours
Best time to visit: June to October (dry season)
Chobe boasts one of the largest concentrations of elephants in Africa. Take a Chobe River cruise for an up-close look at hippos, crocodiles, and big game coming down to drink. It’s an excellent addition to a Victoria Falls itinerary.
Top experiences: Boat safaris, game drives, photography safaris
Best time to visit: May to October
Best for: Walking safaris, leopard sightings, off-the-beaten-path safaris
Known as the birthplace of walking safaris, South Luangwa is perfect for adventurous travelers seeking immersive, guided walks through the bush. The park is teeming with wildlife and is especially famous for its leopard population.
Top experiences: Walking safaris, night drives, rustic bush camps
Best time to visit: July to October
Choose the right season: Dry seasons are generally best for wildlife viewing.
Pick your safari style: Luxury lodge, mobile camping, self-drive, or walking safari?
Book early: Especially for peak seasons like the Great Migration.
Consider combining destinations: Like Kenya & Tanzania, or Botswana & Victoria Falls.
Whether you’re drawn to the epic migration herds of the Serengeti, the rugged beauty of Namibia, or the exclusive wetlands of the Okavango Delta, the best safari in Africa is waiting for you. Every destination offers something unique, and with the right planning, your dream of experiencing a wildlife safari in Africa can become a reality.
Ready to book your African safari tour? Explore our recommended itineraries, expert guides, and travel tips to start planning the adventure of a lifetime.
Visiting Africa as a dentist isn’t just a trip—it’s a transformation. Whether you’re yearning to serve, seeking fresh inspiration, or simply looking for something beyond the everyday grind, a journey like this offers unmatched perspective and purpose.
Through programs like Safari N Smiles, you can blend clinical impact with cultural immersion, CE credit with soul-filling adventure. You’ll return home not just as a better dentist, but as a more connected, fulfilled version of yourself.
So don’t wait for the “perfect time.” The opportunity to make a difference—and rediscover your why—is waiting for you in Africa.
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Our next trip leaves January 2026, and we’d love for you to join us.
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Karen O'Keefe04/10/2024Trustindex verifies that the original source of the review is Google. Egypt 2023-- Amazing adventure and wonderful people involved. This is geared towards dental professionals but I am not one of them. Thoroughly enjoyed myself and Morris makes every trip a memorable experience for everyone! Katy Nierman08/09/2024Trustindex verifies that the original source of the review is Google. Great experience! Saw the big 5 and much more. Thank you, Morris, Keshy, David and everyone behind the scenes! Gloria Herbert06/09/2024Trustindex verifies that the original source of the review is Google. What a sensational trip to Ghana! This was my first mission trip and I was unsure what to expect. It turned out to be a fantastic and humbling experience. Morris and his team put together a very well organized schedule mixing charity work with sightseeing and leisure time. The small group of professionals worked so well together it was amazing to see them in action. I am ready to go again and pitch in where I can. I highly recommend these folks for your next tour. Thanks again Morris. Take a bow! #ghana2024 Omar Hamdy06/09/2024Trustindex verifies that the original source of the review is Google. Amazing team and they do tremendous work overseas! Highly recommend!! Tanya Woods06/09/2024Trustindex verifies that the original source of the review is Google. I was so touched by the Community Service Day whole in Ghana, West Africa. Safari and Smiles was well prepared and organized. So many people were helped. harun anzia05/09/2024Trustindex verifies that the original source of the review is Google. It was an amazing experience. Laura B08/06/2024Trustindex verifies that the original source of the review is Google. I just co-hosted the latest Safari N Smiles trip with founder, Morris. Getting to see some of the behind-the-scenes work in action was such a treat. Not only are SNS creating beautiful and amazing experiences for travelers, but they also care deeply about the impact they can create to support the people of Kenya and other African nations. With a trip of 20 people, everything felt seamless and very personal. We were picked up by team members from the airport, and the rest was taken care of. The moment we arrived, we were taken care of. From life-changing safari adventures in the Maasai Mara to a beautiful few days at the Indian Ocean in Diani Beach, this trip is one that will always be a top memory. Thanks to the Safari N Smiles team-- Morris, Keshy, Joseph, and Robinson for being such kind people and for taking such good care of all of our guests! Kiri-Gabriella26/05/2024Trustindex verifies that the original source of the review is Google. I recently had the pleasure of joining Safari N Smiles in Kenya, and it was an absolutely incredible experience! The trip was exceptionally well-organized, with the perfect balance of thrilling activities and relaxation so there was never a dull moment. One of the highlights was experiencing the Masai Mara from a hot air balloon at sunrise - truly a once-in-a-lifetime moment. The safaris themselves were breathtaking, with knowledgeable staff who enhanced our experience with their expertise and passion for wildlife. The food throughout the trip was second to none and the accommodation was great. I also had the opportunity to connect with like-minded innovators who have became good friends along the way. This trip was worth every penny, leaving me with unforgettable memories and a deep appreciation for the beauty of Kenya. I highly recommend Safari N Smiles for anyone looking to combine their dental career with the adventure of a lifetime, it's worth every penny!